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A self-assembled peptide nucleic acid–microRNA nanocomplex for dual modulation of cancer-related microRNAs.

Authors :
Wang, Xingxing
Xiao, Xiao
Zhang, Bingsen
Li, Jinbo
Zhang, Yan
Source :
Chemical Communications. 2/18/2019, Vol. 55 Issue 14, p2106-2109. 4p.
Publication Year :
2019

Abstract

Here, we report a new strategy for the construction of a peptide nucleic acid–microRNA nanocomplex with dual function to simultaneously suppress oncogenic microRNAs and upregulate tumor-suppressive microRNAs in target cancer cells. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
55
Issue :
14
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
134648359
Full Text :
https://doi.org/10.1039/c9cc00002j