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Severe facial necrosis in a type 1 diabetic patient secondary to mucormycosis masquerading as an internal maxillary artery occlusion: a case report.

Authors :
Manji, Farheen
Lam, John C.
Meatherall, Bonnie L.
Church, Deirdre
Missaghi, Bayan
Source :
BMC Infectious Diseases. 2/22/2019, Vol. 19 Issue 1, pN.PAG-N.PAG. 1p. 1 Color Photograph, 1 Diagram.
Publication Year :
2019

Abstract

<bold>Background: </bold>Mucormycosis is a group of rare but life threatening angioinvasive infections caused by fungi of the order Mucorales that often occurs in immunocompromised patients and individuals with poorly controlled diabetes. Rhinocerebral mucormycosis can mimic sinusitis but can rapidly progress to deeper disease and cause facial necrosis. Facial vascular thrombosis is a rare complication of mucormycosis and can confound diagnosis of the disease.<bold>Case Presentation: </bold>We report the case of a 25-year-old female with poorly controlled type 1 diabetes mellitus who initially presented with symptoms of sinusitis but rapidly progressed with signs of left-sided facial necrosis due to occlusion of the left internal maxillary artery. Early surgical debridement did not yield a microbiological diagnosis. Deeper surgical debridements ultimately revealed angioinvasive fungal disease consistent with mucormycosis. The patient recovered after repeated surgical intervention and aggressive parenteral antifungal therapy.<bold>Conclusion: </bold>This case illustrates an atypical complication of mucormycosis, and emphasizes that a high index of suspicion in vulnerable patient populations aids in the diagnosis of this life-threatening infection. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14712334
Volume :
19
Issue :
1
Database :
Academic Search Index
Journal :
BMC Infectious Diseases
Publication Type :
Academic Journal
Accession number :
134865281
Full Text :
https://doi.org/10.1186/s12879-019-3822-9