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The effect of some chlorhexidine- containing mouthrinses on salivary bacterial counts.
- Source :
-
Journal of Clinical Periodontology . Feb1991, Vol. 18 Issue 2, p90-93. 4p. - Publication Year :
- 1991
-
Abstract
- A number of chlorhexidine mouthwashes are available commercially which differ in formulation and regimen of use. As a comparative measure of antimicrobial persistance, this study evaluated the effect of 4 chlorhexidine mouthwash formulations on salivary bacterial counts after a single rinse. The study was a randomised single-examiner blind 5-way crossover investigation employing a panel of 10 young healthy human volunteers. The 0.12% and 0.2% commercial formulations when rinsed according to the respective manufacturers instructions produced similar large and prolonged reductions in salivary bacterial counts during the 7-h period. A 0.1% formulation also commercially available produced minimal effects on salivary bacterial counts and was little different to the saline rinse. A reformulated 0.1% rinse, not commercially available at the time of the study, produced significant salivary bacterial count reductions over the 7-h period albeit to a lesser degree of magnitude than to the 0.2% and 0.12% rinses. The results were consistent with comparative plaque inhibitory studies of the formulations and suggest that the method is a quick and simple way of screening products for antimicrobial and antiplaque potential. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03036979
- Volume :
- 18
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Clinical Periodontology
- Publication Type :
- Academic Journal
- Accession number :
- 13491270
- Full Text :
- https://doi.org/10.1111/j.1600-051X.1991.tb01694.x