Radiochemical isolation method for the production of 52gMn from natCr for accelerator targets.

Abstract We report a novel, precipitation-based method for the isolation of Mn from Cr targets for cyclotron production of 52gMn. The separation produces no-carrier-added 52gMn with a decay corrected radiochemical yield of 85 ± 3% and apparent molar activity for DOTA of 1.3 GBq/μmol. This method reduces stable metallic impurities in the purified 52gMn compared to previously reported chromatographic methods. Highlights • Radiochemical separation using a 2-phase precipitation method and single extraction chromatography column. • Separation strategy for production no-carrier-added 52gMn. • Process allows for chelation studies with DOTA. [ABSTRACT FROM AUTHOR]