Recent advances in chemiluminescence for reactive oxygen species sensing and imaging analysis.

Abstract In this article, we reviewed the current state of chemiluminescence in reactive oxygen species (ROS) sensing and imaging with 132 references. The review is divided into three main sections. The first focuses on the various strategies used in ROS sensing and imaging; the second is organized by a series of detections and applications for five ROS, including hydrogen peroxide, hydroxyl radical, superoxide radical, singlet oxygen and peroxynitrite; and the last covers two individual ROS (hydrogen peroxide and superoxide radical) imaging and multiplex imaging (hydrogen peroxide and adenosine triphosphate, peroxynitrite or β -galactosidase) not only in vitro but also in vivo. Finally, the future trend is discussed. Highlights • In this article, we reviewed the current state of chemiluminescence in reactive oxygen species (ROS) sensing and imaging; • The first focuses on the various strategies used in ROS sensing and imaging; • The second is organized by a series of detections and applications for ROS; • The last covers ROS imaging; • The future trend is discussed. [ABSTRACT FROM AUTHOR]