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Sex difference in the incidence of stroke and its corresponding influence factors: results from a follow-up 8.4 years of rural China hypertensive prospective cohort study.
- Source :
-
Lipids in Health & Disease . 3/25/2019, Vol. 18 Issue 1, pN.PAG-N.PAG. 1p. 1 Diagram, 4 Charts, 1 Graph. - Publication Year :
- 2019
-
Abstract
- Background: Few studies investigate sex difference in stroke incidence in rural China hypertensive population. Methods: A total of 5097 hypertensive patients aged ≥35 years (mean age, 56.3 ± 11.2 years; 43.8% men) were included in our analysis with a median follow-up 8.4 years in Fuxin county of Liaoning province in China. Cox proportional hazard models were used to analyze the association between the potential factors and incident stroke. Results: We observed 501 new strokes (310 ischemic, 186 hemorrhagic, and 5 unclassified stroke) during the follow-up. The overall incidence of stroke was 1235.21 per 100,000 person-years; for men, the rates were 1652.51 and 920.80 for women. This sex difference in all stroke can be explained by approximately 25% through age, systolic blood pressure, body mass index, low-density lipoprotein-cholesterol, current smoking, current drinking, antihypertensive drugs, education and physical activity. Subgroup analysis indicated that in hemorrhagic stroke this sex difference was more remarkable (63.89% can be explained). Conclusions: The incidence of stroke was higher in men than that in women and this difference was partly explained by several traditional cardiovascular risk factors. [ABSTRACT FROM AUTHOR]
- Subjects :
- *STROKE
*PUBLIC health
*HYPERTENSION
*COHORT analysis
Subjects
Details
- Language :
- English
- ISSN :
- 1476511X
- Volume :
- 18
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Lipids in Health & Disease
- Publication Type :
- Academic Journal
- Accession number :
- 135534260
- Full Text :
- https://doi.org/10.1186/s12944-019-1010-y