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Rhodamine derivatives as selective"naked-eye" colorimetric and fluorescence off-on sensor for Hg2+ in aqueous solution and its applications in bioimaging.
- Source :
-
Journal of Luminescence . May2019, Vol. 209, p411-419. 9p. - Publication Year :
- 2019
-
Abstract
- Abstract Three new rhodamine based probes 1 , 2 , 3 were synthesized and acted as fluorescence probes for Hg2+ detection in Tris - HCl/C 2 H 5 OH (v : v = 3: 7, 10 mM, pH = 7.2). Hg2+ induced a colorless solution of probes 1 , 2 , 3 to turn to naked-eye visible pink with a 44 - fold fluorescence enhancement at 576 nm. Probes 1 , 2 , 3 are highly selective to Hg2+ over other tested cations with the detection limits are 18 nM, 16 nM, 56 nM, respectively. What's more, the binding constants between probes 1 , 2 , 3 and Hg2+ are 5.0 × 106 M−1, 1.8 × 106 M−1, 1.5 × 106 M−1, respectively. The different detection limits and binding constants of probes 1 , 2 , 3 and Hg2+ may depend on the coordination of probes 1 , 2 , 3. The recognition mechanism of probes 1 , 2 , 3 towards Hg2+ is determinated by ESI - MS, DFT and indicates that a ring-opening of the spirolactam unit and formed complexes between probes 1 , 2 , 3 , resulting in chromogenic and fluorogenic changes. The probes 1 , 2 , 3 could be applied in both environmental and Hg2+ polluted samples due to the instantly and reversible "off-on" Hg2+ response, well cell permeability, cell imaging ability. Graphical abstract Rhodamine based "turn-on" chemodosimeter exhibited instant/reversible and excellent specificity towards Hg2+ in aqueous media and living cells. fx1 [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00222313
- Volume :
- 209
- Database :
- Academic Search Index
- Journal :
- Journal of Luminescence
- Publication Type :
- Academic Journal
- Accession number :
- 135596664
- Full Text :
- https://doi.org/10.1016/j.jlumin.2019.02.024