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Distinct Lipid Transfer Proteins display different IgE‐binding activities that are affected by fatty acid binding.

Distinct Lipid Transfer Proteins display different IgE‐binding activities that are affected by fatty acid binding.

Authors :
Aina, Roberta
Dubiela, Pawel
Geiselhart, Sabine
Bublin, Merima
Bruschi, Maurizio
Radauer, Christian
Nagl, Christoph
Humeniuk, Piotr
Asero, Riccardo
Mortz, Charlotte Gotthard
Hafner, Christine
Hoffmann‐Sommergruber, Karin
Borowski, Tomasz
Source :
Allergy. Apr2019, Vol. 74 Issue 4, p827-831. 5p. 1 Diagram, 1 Graph.
Publication Year :
2019

Abstract

The article discusses a study which examines the Immunoglobulin E (IgE) binding activities of nonspecific lipid transfer proteins (nsLTPs) affected by fatty acid binding. Topics include the impact of fatty acid interaction in the allergenic properties of nsLTPs, the differences in the epitope structure of IgE which led to different, higher and lower IgE binding activities and the changes in the accessibility of the epitopes upon ligand binding.

Details

Language :
English
ISSN :
01054538
Volume :
74
Issue :
4
Database :
Academic Search Index
Journal :
Allergy
Publication Type :
Academic Journal
Accession number :
135666012
Full Text :
https://doi.org/10.1111/all.13682