Preparation of surface imprinted polymers and its application n drug separation analysis.

The surface molecular imprinting technique is to polymerize and establish the molecular recognition site on the outer layer or surface of the carrier. As a result, the surface molecularly imprinted polymers have the advantages of fast binding speed, strong identification selectivity, high binding capacity and improved efficiency of imprinted materials. In this paper, the principle of surface molecularly imprinted polymers and four preparation methods (sol-gel method, graft copolymerization method, sacrificial carrier method, polymerization plus membrane method, active controllable free radical polymerization) were briefly introduced. Four aspects of drug separation and analysis (traditional Chinese medicine extraction and separation; drug sensors; chiral drug resolution; the application) in drug release was reviewed. [ABSTRACT FROM AUTHOR]