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A multifunctional persistent luminescent nanoprobe for imaging guided dual-stimulus responsive and triple-synergistic therapy of drug resistant tumor cells.
- Source :
-
Chemical Communications . 5/8/2019, Vol. 55 Issue 36, p5283-5286. 4p. - Publication Year :
- 2019
-
Abstract
- We report the design and fabrication of a multifunctional persistent luminescent nanoprobe for imaging guided dual-stimulus responsive and triple-synergistic therapy of drug resistant tumor. The integration of the dual-stimulus of an acidic microenvironment and laser irradiation with the triple-synergistic therapy of doxorubicin, photothermal and siRNA offers excellent therapeutic performance for drug resistant tumor cells with high specificity and little side effects. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DRUG therapy
*DRUG side effects
*DOXORUBICIN
*SMALL interfering RNA
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 55
- Issue :
- 36
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 136143878
- Full Text :
- https://doi.org/10.1039/c9cc01446b