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DNA microarray analysis of normal rat kidney epithelial cells treated with cadmium.

Authors :
Maki Tokumoto
Tomoaki Ohtsu
Akiko Honda
Yasuyuki Fujiwara
Hisamitsu Nagase
Masahiko Satoh
Source :
Journal of Toxicological Sciences. 1/1/2011, Vol. 36 Issue 1, p127-129. 3p. 2 Charts.
Publication Year :
2011

Abstract

In order to elucidate the transcriptional response of kidney epithelial cells to cadmium, the gene expression pattern was examined in normal rat kidney epithelial cells (NRK-52E cells) exposed to 50 μM cadmium for 4 hr using DNA microarray. Cadmium was found to increase the expression of 73 genes and decrease the expression of 42 genes in NRK-52E cells before the development of cytotoxicity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03881350
Volume :
36
Issue :
1
Database :
Academic Search Index
Journal :
Journal of Toxicological Sciences
Publication Type :
Academic Journal
Accession number :
136165770
Full Text :
https://doi.org/10.2131/jts.36.127