Iodine‐promoted Intermolecular Dehydrogenation Diamination: Synthesis of Unsymmetrical α,β‐Diamido Ketones.

Iodine‐promoted direct diamination of α,β‐unsaturated ketone to form two C−N bonds has been developed starting from chalcone and secondary amine. This reaction was performed in THF at 50 °C in the presence of I2 and K2CO3. The protocol is metal‐free, operationally simple and carried out under mild conditions, providing an effective new way for directing diamination reactions. [ABSTRACT FROM AUTHOR]