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Cost-effectiveness of an intervention to reduce fear of cancer recurrence: The ConquerFear randomized controlled trial.
- Source :
-
Psycho-Oncology . May2019, Vol. 28 Issue 5, p1071-1079. 9p. 2 Charts, 2 Graphs. - Publication Year :
- 2019
-
Abstract
- <bold>Objective: </bold>Alongside a randomized controlled trial (RCT) evaluating the efficacy of the ConquerFear intervention for reducing fear of cancer recurrence in cancer survivors, the cost-effectiveness of this novel intervention was assessed, primarily from the health sector perspective, with broader societal productivity impacts assessed.<bold>Methods: </bold>Health care resource use was collected by a tailored cost diary. Incremental costs were calculated as the difference in total costs between the intervention and control groups. Incremental cost-effectiveness ratios (ICERs) were estimated by cost-effectiveness and cost-utility analyses, comparing incremental costs with incremental outcomes measured. Nonparametric bootstrap analysis was performed to evaluate uncertainty in costs and outcomes.<bold>Results: </bold>Cancer survivors were randomized into ConquerFear (n = 121), or an active control group receiving relaxation training (n = 101). Participants received on average 3.69 sessions, incurring an average cost of $297 per person, with no group difference. The ITT analysis results indicated a mean ICER $34 300 per quality-adjusted life year (QALY) with average incremental cost $488 and health gain of 0.0142 QALYs, from the health care sector perspective. Bootstrap analysis showed 30% of iterations were dominant and overall 53% ICERs were cost-effective as judged by the commonly used $50 000/QALY threshold.<bold>Conclusions: </bold>The ConquerFear intervention is associated with a modest cost and may provide good value for money, but further evidence is needed. Long-term cost-effectiveness needs further investigation to capture full benefits from the intervention beyond the trial follow-up. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10579249
- Volume :
- 28
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Psycho-Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 136270527
- Full Text :
- https://doi.org/10.1002/pon.5056