Back to Search
Start Over
Prognostic efficacy of C-reactive protein/albumin ratio in ST elevation myocardial infarction.
- Source :
-
Scandinavian Cardiovascular Journal . Apr2019, Vol. 53 Issue 2, p83-90. 8p. - Publication Year :
- 2019
-
Abstract
- <bold>Objective: </bold>Although the prognostic efficacy of C-reactive protein (mg/L) and albumin levels (g/L) has been previously associated with poor prognosis in ST elevation myocardial infarction (STEMI), to the best of our knowledge, the prognostic efficacy of C-reactive protein/Albumin ratio (CAR) (mg/g) has not been investigated yet. Thus, this study aimed to investigate the potential efficacy of the CAR in predicting prognosis in STEMI patients.<bold>Method: </bold>We conducted a detailed investigation of 2437 patients with first STEMI treated with a primary percutaneous coronary intervention. After evaluation regarding to exclusion criteria, 2243 patients were found to be eligible for analysis. The mean follow-up of the study was 34 ± 15 months.<bold>Results: </bold>The median CAR value of the study population was 2.70 (range: 1.44-4.76), and the patients were divided into three tertiles according to their CAR values. Kaplan-Meier survival analysis showed significantly lower in-hospital and long-term survival rates for the patients in a high CAR tertile. In addition, the CAR was found to be an independent predictor of all-cause mortality (Hazards ratio: 1.033, 95% Confidence Interval: 1.007-1.061, p = .033), and the prognostic performance of the CAR was superior to that of C-reactive protein, albumin, and neutrophil to lymphocyte ratio in the receiver operating characteristic curve comparison.<bold>Conclusion: </bold>The CAR, a newly introduced inflammation-based risk index, was found to be a potentially useful prognostic tool for predicting a poor prognosis in STEMI patients. However, this finding needs to be validated in the future prospective studies. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14017431
- Volume :
- 53
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Scandinavian Cardiovascular Journal
- Publication Type :
- Academic Journal
- Accession number :
- 136555333
- Full Text :
- https://doi.org/10.1080/14017431.2019.1590628