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A small-molecule probe for ratiometric photoacoustic imaging of hydrogen sulfide in living mice.

Authors :
Li, Xiang
Tang, Yufu
Li, Jie
Hu, Xiaoming
Yin, Chao
Yang, Zhen
Wang, Qi
Wu, Zizi
Lu, Xiaomei
Wang, Wenjun
Huang, Wei
Fan, Quli
Source :
Chemical Communications. 5/25/2019, Vol. 55 Issue 42, p5934-5937. 4p.
Publication Year :
2019

Abstract

A small-molecule photoacoustic probe based on cyanine dyes was developed by taking advantage of the nucleophilic substitution reaction of H2S with chlorine. The probe demonstrated specific response to H2S with ratiometric photoacoustic signals in the NIR region, which enabled real-time, accurate, high-resolution imaging of endogenous H2S in vivo. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
55
Issue :
42
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
136560344
Full Text :
https://doi.org/10.1039/c9cc02224d