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Impact of transcranial magnetic stimulation on the symptom profile of major depressive episode.
- Source :
-
Australasian Psychiatry . Jun2019, Vol. 27 Issue 3, p297-301. 5p. - Publication Year :
- 2019
-
Abstract
- <bold>Objectives: </bold>This study aimed to explore the effects of a four-week course of transcranial magnetic stimulation (TMS) on the following symptoms of major depressive episode (MDE): mood, work activities, health concerns, guilt, anxiety and retardation.<bold>Method: </bold>Patients underwent 20 daily sessions of 10 Hz TMS (two sets of 10 daily treatments separated by two days of rest). The six-item Hamilton Depression Rating Scale (HAMD-6) was administered before and after treatment. Remission was operationalised as a HAMD-6 score of <4. Descriptive statistics and t-tests were used to compare pre/post scores on HAMD-6 subscales, and logistic regression was used to understand symptoms that predicted remission/non-remission.<bold>Results: </bold>There were 104 participants (79 female; 76%), with a mean age of 44.6 years (SD=15.7 years). There was a significant improvement in the whole sample and in remitters (n=70) on all subscales. However, those who failed to remit did not achieve significant reductions in 'health concerns' and 'retardation'. There were no difference in age and sex between remitters and non-remitters. Also, there were no significant differences between the remitters and non-remitters on the pretreatment depression symptom profiles. No predictors of response were identified, as expected.<bold>Conclusions: </bold>TMS has the ability to reduce all listed MDE symptoms. No pretreatment MDE symptom profile was identified which might carry prognostic value. [ABSTRACT FROM AUTHOR]
- Subjects :
- *TRANSCRANIAL magnetic stimulation
*HAMILTON Depression Inventory
*AGE differences
Subjects
Details
- Language :
- English
- ISSN :
- 10398562
- Volume :
- 27
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Australasian Psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 137001673
- Full Text :
- https://doi.org/10.1177/1039856219828134