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Study Insights into Gastrointestinal Cancer through the Gut Microbiota.
- Source :
-
BioMed Research International . 6/24/2019, p1-8. 8p. - Publication Year :
- 2019
-
Abstract
- The gut microbiome in human is recognized as a "microbial organ" for its roles and contributions in regulating the human homeostasis and metabolism. Gastrointestinal (GI) cancers, especially colorectal cancer (CRC), rank as the most common cancer-related deaths worldwide. Evidences have suggested that the disorder of gut microbiota, also named as "dysbiosis," is related to the development of a variety of diseases such as inflammatory bowel disease (IBD) and the CRC. However, detailed mechanisms between disease and gut microbiota remain largely unknown. This review introduced the correlation between gastrointestinal diseases and the microbiota in human gut from the recent studies, as well as the roles of microbiota in manipulating the CRC and IBDs development, in order to facilitate future studies and to develop novel methods for the precaution, diagnosis, or even cure of gastrointestinal diseases. Additionally, we also elucidated the possibility of probiotics in treatment against CRC. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GASTROINTESTINAL disease diagnosis
*GASTROINTESTINAL disease prevention
*INFLAMMATORY bowel diseases
*THERAPEUTIC use of probiotics
*GASTROINTESTINAL tumors
*COLON tumors
*GASTROINTESTINAL diseases
*HOMEOSTASIS
*GUT microbiome
*DISEASE risk factors
*TUMOR risk factors
*CANCER risk factors
RECTUM tumors
Subjects
Details
- Language :
- English
- ISSN :
- 23146133
- Database :
- Academic Search Index
- Journal :
- BioMed Research International
- Publication Type :
- Academic Journal
- Accession number :
- 137137995
- Full Text :
- https://doi.org/10.1155/2019/8721503