SA61CAN DNA METHYLATION PROFILING SHED LIGHT ON THE BIOLOGY OF CANNABIS ASSOCIATED PSYCHOSIS? PRELIMINARY DATA ON THE EWAS CANNABIS USE SIGNATURE IN THE EUGEI CASE-CONTROL STUDY.

Highlights from the article: Sa61can dna methylation profiling shed light on the biology of cannabis associated psychosis? B Results: b Our preliminary analyses revealed regular cannabis use-associated dysregulation of DNA methylation at multiple loci across the epigenome that also include CpGs previously associated with Schizophrenia. B Discussion: b This epigenome-wide study of first episode psychosis patients and healthy controls represents the largest and most comprehensive study of methylomic variation in regular cannabis users compared to never users performed to date.