SU109IS THE ERA OF CANDIDATE GENES X CANNABIS USE REALLY DEAD?

Highlights from the article: B Background: b Historically, gene X environment examinations in psychotic disorders have employed candidate gene methods and environmental determinants impacting on similar biological mechanisms. Indeed, candidate gene approaches might be complementary to GWAS to test gene X cannabis interaction. B Discussion: b Our results suggest that dopamine signaling is implicated in cannabis associated psychosis, and, more specifically, that variation within the DRD2 gene may modulate the effect of cannabis use on psychosis phenotypes.