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Silver Triflate Catalyzed Synthesis of Isoquinolino[2,1- a ]quinazo-lino[3,2- c ]quinazoline Derivatives via Alkyne Hydroamination.
- Source :
-
Synthesis . 2019, Vol. 15 Issue 16, p3101-3108. 8p. - Publication Year :
- 2019
-
Abstract
- Using 2-(2-aminophenyl)quinazolin-4(3 H)-one and 2-(2-phenylethynyl)benzaldehyde as the reactants, silver triflate (AgOTf) was proved to be an efficient catalyst to promote not only quinazoline cyclization, but also the intramolecular hydroamination of alkyne for the synthesis of 6-aryl-17 H ,18a H -isoquinolino[2,1- a ]quinazolino[3,2- c ]quinazolin-17-one derivatives in high yields. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYDROAMINATION
*ALKYNE derivatives
*ISOQUINOLINE
*BENZALDEHYDE
*SILVER
*QUINAZOLINE
Subjects
Details
- Language :
- English
- ISSN :
- 00397881
- Volume :
- 15
- Issue :
- 16
- Database :
- Academic Search Index
- Journal :
- Synthesis
- Publication Type :
- Academic Journal
- Accession number :
- 137827268
- Full Text :
- https://doi.org/10.1055/s-0037-1611808