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Association between overweight or obesity and the risk for childhood asthma and wheeze: An updated meta‐analysis on 18 articles and 73 252 children.
- Source :
-
Pediatric Obesity . Sep2019, Vol. 14 Issue 9, pN.PAG-N.PAG. 1p. - Publication Year :
- 2019
-
Abstract
- Summary: Background: Overweight or obesity is increasingly recognized as a possible risk factor for childhood asthma. Objectives: We aimed to meta‐analyse the association between overweight or obesity and the risk for childhood asthma and wheeze and meanwhile explore potential causes of between‐study heterogeneity. Methods: Literature search, study selection, and data extraction were performed independently and in duplicate. Data were analysed by STATA software. Results: Eighteen articles and 73 252 children were analysed. In overall analyses, there was a significant association between overweight or obesity and the risk for childhood asthma (odds ratio [OR] = 1.30; 95% confidence interval [CI], 1.23‐1.39; P < 0.001) and wheeze (OR = 1.90; 95% CI, 1.38‐2.63; P < 0.001), with none/marginal publication bias as revealed by the Egger test (P = 0.938/0.038), respectively. Subgroup analyses showed that children with obesity (OR = 1.40; 95% CI, 1.29‐1.52) were more likely to have asthma than children with overweight (OR = 1.22; 95% CI, 1.14‐1.31), and in children with overweight or obesity, girls (OR = 1.34; 95% CI, 1.16‐1.56) were more likely to have asthma than boys (OR = 1.27; 95% CI, 1.15‐1.40). Conclusions: Our findings indicate that overweight or obesity is a significant risk factor for childhood asthma and wheeze and in children with overweight or obesity, the risk is more evident in girls than in boys. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ASTHMA prevention
*ASTHMA risk factors
*CONFIDENCE intervals
*MEDICAL information storage & retrieval systems
*MEDLINE
*META-analysis
*CHILDHOOD obesity
*ONLINE information services
*RESPIRATORY organ sounds
*SEX distribution
*SYSTEMATIC reviews
*DATA analysis software
*ODDS ratio
*DISEASE complications
*CHILDREN
Subjects
Details
- Language :
- English
- ISSN :
- 20476302
- Volume :
- 14
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Pediatric Obesity
- Publication Type :
- Academic Journal
- Accession number :
- 137906779
- Full Text :
- https://doi.org/10.1111/ijpo.12532