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Safety and efficacy of microwave ablation for benign thyroid nodules and papillary thyroid microcarcinomas: A systematic review and meta-analysis.
- Source :
-
European Journal of Radiology . Sep2019, Vol. 118, p58-64. 7p. - Publication Year :
- 2019
-
Abstract
- <bold>Purpose: </bold>To summarize the published literature on microwave ablation (MWA) for the treatment of benign thyroid nodules and papillary thyroid microcarcinomas, and to evaluate the effectiveness and safety of MWA as a novel treatment strategy.<bold>Methods: </bold>Two independent authors carried out the literature search using four databases, including PubMed, Embase, Cochrane, and Web of Science. The meta-analysis included prospective and retrospective data that compared pre-treatment values to post-treatment outcomes.<bold>Results: </bold>From the 33 original articles, seven studies met the inclusion criteria for this meta-analysis. Of these, five were retrospective studies, two were prospective trials, one was controlled study, and one was a multi-center study. The results showed significant improvements in nodule volume, clinical symptom scores, and beauty scores between the baseline and final follow-up visits. In all of the studies, the most common adverse effects were hematomas, unbearable pain, and transient or permanent voice change in 3.8%, 2.2%, and 4.6% of patients, respectively. None of these incidents resulted in hospitalization or death.<bold>Conclusions: </bold>MWA is effective and safe for the treatment of benign thyroid nodules and papillary thyroid microcarcinomas. However, future studies should compare the efficacy of MWA, RFA, and surgical intervention. [ABSTRACT FROM AUTHOR]
- Subjects :
- *META-analysis
*MICROWAVES
*HEMATOMA
*RETROSPECTIVE studies
Subjects
Details
- Language :
- English
- ISSN :
- 0720048X
- Volume :
- 118
- Database :
- Academic Search Index
- Journal :
- European Journal of Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 138128284
- Full Text :
- https://doi.org/10.1016/j.ejrad.2019.06.027