LncRNA LINC00668 promotes the progression of breast cancer by inhibiting apoptosis and accelerating cell cycle.

Highlights from the article: By transfection of sh-LINC00668 in BC cells, proliferation, apoptosis, cell LINC00668 knockdown in BC cells induced apoptosis and arrested cell cycle. Abbreviations: BC, breast cancer; GSEA, Gene set enrichment analysis; TCGA, The Cancer Genome Atlas. (B) Transfection of sh-LINC00668 1# and sh-LINC00668 4# in BC cells inhibited AKT/mTOR pathway.