A subcutaneous nodule in a returning Chinese expatriate.

I volvulus i infection is endemic generally have a lower possibility of skin microfilariae and less ocular disease than do visitors to these regions [[3]]. A clinical suspicion of onchocerciasis should be evoked when travelers from endemic regions have skin lesions compatible with the disease. A diagnosis of onchocerciasis is usually based on the presence of microfilariae in superficial skin shavings or a punch biopsy, with adult worms in histologic sections of excised nodules. I volvulus i is associated with the essential endosymbiotic bacterium I Wolbachia i , anti- I Wolbachia i therapies (including doxycycline) are an evolving treatment strategy for onchocerciasis [[4]]. [Extracted from the article]