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Short-term impact of breast cancer screening intervention on health-related quality of life in China: A multicentre cross-sectional survey.
- Source :
-
Psycho-Oncology . Sep2019, Vol. 28 Issue 9, p1836-1844. 9p. 3 Charts, 1 Graph. - Publication Year :
- 2019
-
Abstract
- <bold>Objective: </bold>The impact of participating in breast cancer screening programmes on health-related quality of life (HRQoL)is poorly understood.<bold>Methods: </bold>Based on a national breast cancer screening programme in China, a multicentre cross-sectional survey was conducted covering 12 provinces from September 2013 to December 2014. HRQoL of participants in the screening population and general population was evaluated by the three-levelEuroQol-five-Dimensions (EQ-5D-3L) instrument, and utility scores were generated through the Chinese value set. Univariate and multivariate regression analyses were performed to explore determinants of utility scores and anxiety/depression problems.<bold>Results: </bold>For screening group and general population (n = 4756, mean age = 51.6 year old), the corresponding utility scores were 0.937 (95% CI, 0.933-0.941) and 0.953 (0.949-0.957) (P < .001). Pain/discomfort and anxiety/depression were the most common reported in both groups (51.4% and 34.3%, P < .001). Utility scores at prescreening, in-screening, and postscreening interview timings were 0.928 (0.921-0.935), 0.958 (0.948-0.969), and 0.938 (0.933-0.943), respectively (P < .001); the corresponding proportions of anxiety/depression reporting were 25.9%, 16.3%, and 21.1%, respectively (P = .004). Interview timing, geographical region, and insurance status were associated with HRQoL and anxiety/depression in women at high-risk of breast cancer.<bold>Conclusions: </bold>Utility scores of screening participants were significantly lower than that of general population in China, but the difference may be clinically insignificant. Further cohort studies using HRQoL measurements are needed. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10579249
- Volume :
- 28
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Psycho-Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 138457245
- Full Text :
- https://doi.org/10.1002/pon.5160