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Management of the N0 neck in patients with laryngeal squamous cell carcinoma.
- Source :
-
Acta Oto-Laryngologica . Oct2019, Vol. 139 Issue 10, p908-912. 5p. - Publication Year :
- 2019
-
Abstract
- Background: Neck lymph node status is the chief prognostic index in patients with head and neck squamous cell carcinoma (SCC), yet the management of a clinically negative neck in this setting is still controversial, especially in patients with laryngeal SCC (LSCC). Objectives: To evaluate the efficacy of selective neck dissection (SND) to control occult disease in patients with LSCC and clinically negative (cN0) necks. Materials and methods: Medical records of 1476 patients with cN0 LSCC were analyzed. In conjunction with primary treatment, 126 (8.5%) underwent at least unilateral elective neck dissection, whereas most 1350 (91.5%) followed a wait-and-see protocol. Prognostic significance was indicated by the Kaplan–Meier survival estimates. Results: The rate of occult neck disease was 15%. Five-year overall and disease-free survival rates were 74.4% and 66.7%, respectively. Prognosis was closely related to T stage, preoperative tracheotomy, and postoperative recurrence. There was no significant correlation with age, sex, or preoperative neck dissection; but in patients with supraglottic LSCC, the relation between prognosis and preoperative neck dissection was significant, with fewer neck and local recurrences than the wait-and-see group (p <.05). Conclusions and significance: Selective neck dissection is serving as an accurate prognostic tool in patients with supraglottic laryngeal cancers. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CANCER relapse
*MEDICAL protocols
*MEDICAL records
*HEAD & neck cancer
*NECK surgery
*SQUAMOUS cell carcinoma
*SURGICAL complications
*SURVIVAL
*TRACHEOTOMY
*TUMOR classification
*DISEASE management
*TREATMENT effectiveness
*PREOPERATIVE period
*KAPLAN-Meier estimator
*ACQUISITION of data methodology
*PROGNOSIS
LARYNGEAL tumors
Subjects
Details
- Language :
- English
- ISSN :
- 00016489
- Volume :
- 139
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Acta Oto-Laryngologica
- Publication Type :
- Academic Journal
- Accession number :
- 138549343
- Full Text :
- https://doi.org/10.1080/00016489.2019.1641219