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Multicomponent Approach to Hydantoins and Thiohydantoins Involving a Deep Eutectic Solvent.
- Source :
-
Chemistry - An Asian Journal . 9/16/2019, Vol. 14 Issue 18, p3188-3197. 10p. - Publication Year :
- 2019
-
Abstract
- We report an efficient synthetic strategy to diverse hydantoins and thiohydantoins involving a three‐component reaction with the aid of deep eutectic solvent. Here, N,N′‐dimethyl urea and N,N′‐dimethyl thiourea play a dual role as reactant and reaction medium along with l‐(+)‐tartaric acid. The three‐component reaction provides an easy access to 5‐amino‐1,3‐dialkyl‐substituted hydantoins and thiohydantoins in good yields. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYDANTOIN
*EUTECTICS
*EUTECTIC reactions
*SOLVENTS
*UREA
Subjects
Details
- Language :
- English
- ISSN :
- 18614728
- Volume :
- 14
- Issue :
- 18
- Database :
- Academic Search Index
- Journal :
- Chemistry - An Asian Journal
- Publication Type :
- Academic Journal
- Accession number :
- 138735667
- Full Text :
- https://doi.org/10.1002/asia.201900744