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Functional Outcome of Elderly Patients Treated for Odontoid Fracture: A Multicenter Study.

Authors :
De Bonis, Pasquale
Iaccarino, Corrado
Musio, Antonio
Martucci, Antonio
De Iure, Federico
Donati, Roberto
Cultrera, Francesco
Tosatto, Luigino
Servadei, Franco
Alesi, Domenico
Cavallo, Michele Alessandro
Ghadirpour, Reza
Molinari, Filippo
Lofrese, Giorgio
Source :
Spine (03622436). 7/1/2019, Vol. 44 Issue 13, p951-958. 8p.
Publication Year :
2019

Abstract

<bold>Study Design: </bold>Retrospective multicenter study.<bold>Objective: </bold>Analysis of impact of conservative and surgical treatments on functional outcome of geriatric odontoid fractures.<bold>Summary Of Background Data: </bold>Treatment of odontoid fractures in aged population is still debatable.<bold>Methods: </bold>One hundred fourty-seven consecutive odontoid fractures in elderly patients were classified according to Anderson-D'Alonzo and Roy-Camille classifications. Philadelphia type collar was always positioned and kept as a treatment whenever acceptable. Halo-vest, anterior screw fixation, C1-C2 posterior arthrodesis, and occipito-cervical fixation were the other treatments adopted. Conservative or surgical treatment strategy was more significantly influenced by antero-posterior displacement (< or >5 mm) and by surgeon decision. On admission ASA, modified Rankin scale (mRS-pre) and Charlson Comorbidity Index (CCI) were assessed. Modified Rankin scale (mRS-post), Neck Disability Index (NDI), and Smiley Webster Pain Scale (SWPS) were administered 12 to 15 months after treatment to estimate functional outcome in terms of general disability, neck-related disability, and ability to return to work/former activity. Risk of treatment crossover was calculated considering factors affecting outcome. Fracture healing process in terms of fusion-stability, no fusion-stability, no fusion-no stability was evaluated at 12 months through a cervical computed tomography (CT) scan. Dynamic cervical spine x-rays were obtained whether necessary. No fusion-stability was considered an adequate treatment goal in our geriatric population. Chi square/Fisher exact test and logistic regression were performed for statistical anal.<bold>Results: </bold>Overall 67 patients were treated conservatively whereas 80 underwent surgery. Collar was adopted in 45 patients, while anterior odontoid fixation and C1-C2 posterior arthrodesis were preferred for 30 patients each. 79.8% of patients showed good outcomes according to NDI. No significant differences were observed between patients of 65 to 79 years and more than or equal to 80 years (P = 0.81). CCI greatly correlated with mRS-post, with higher indexes in 68.8% of cases characterized by good outcomes (P = 0.05). mRS-pre correlated with NDI (P < 0.000001) and mRS-post (P = 0.04). CCI, mRS-pre, and surgery were associated with worse NDI, while both C1-C2 posterior arthrodesis and occipito-cervical stabilization were associated with worse mRS-post, respectively in 40% and 30% of cases. Younger patients had a higher risk of treatment crossover.<bold>Conclusion: </bold>mRS-pre and CCI provided two independent predictive values respectively for functional outcome and post-treatment disability. Compared with conservative immobilizations, surgery revealed no advantages in the elderly in terms of functional outcome.<bold>Level Of Evidence: </bold>3. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03622436
Volume :
44
Issue :
13
Database :
Academic Search Index
Journal :
Spine (03622436)
Publication Type :
Academic Journal
Accession number :
138772466
Full Text :
https://doi.org/10.1097/BRS.0000000000002982