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Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir1.

Authors :
Mishin, Vasiliy P.
Patel, Mira C.
Chesnokov, Anton
De La Cruz, Juan
Ha T. Nguyen
Lollis, Lori
Hodges, Erin
Yunho Jang
Barnes, John
Uyeki, Timothy
Davis, Charles T.
Wentworth, David E.
Gubareva, Larisa V.
Nguyen, Ha T
Jang, Yunho
Source :
Emerging Infectious Diseases. Oct2019, Vol. 25 Issue 10, p1969-1972. 4p.
Publication Year :
2019

Abstract

Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10806040
Volume :
25
Issue :
10
Database :
Academic Search Index
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
138838696
Full Text :
https://doi.org/10.3201/eid2510.190607