GENETICS OF SEVERE MENTAL ILLNESS IN A COLOMBIAN POPULATION ISOLATE.

B Overall Abstract: b Our current classification system divides severe mental illness (SMI) into dichotomous diagnostic categories; psychotic disorders and mood disorders. Dr. Carlos Lopez will present the Paisa project, including the sample diagnosis-naïve recruitment strategy and deep and uniform phenotyping, which involves diagnostic interview, symptom assessment and a neurocognitive battery. Dr. Carrie Bearden will present results from the Spanish-language Penn Computerized Neurocognitive Battery, evaluating contributions of both diagnosis and symptom domains to cognitive performance. [Extracted from the article]