S54EPIGENOME-WIDE DNA METHYLATION PROFILES PRE- AND POST ECT.

B Background: b Electroconvulsive therapy (ECT) is the treatment of choice for severe and treatment-resistant depression. B Methods: b In this study, we analysed epigenome-wide DNA methylation of 34 severely depressed patients before and after ECT treatment using the Illumina Infinium Methylation BeadChip which contains >850.000 CpG sites. B Discussion: b This is the first feasibility study analyzing methylation profiles in patients with severe and treatment resistant depression before and after ECT. [Extracted from the article]