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Common methodological pitfalls and new developments in systematic review meta‐analyses.
- Source :
-
British Journal of Dermatology . Oct2019, Vol. 181 Issue 4, p649-651. 3p. - Publication Year :
- 2019
-
Abstract
- Systematic reviews have become an increasingly popular tool to assess best evidence and have an established place at the top of the evidence pyramid, above individual randomized controlled trials (RCTs). Meta-analyses are useful as they provide estimates of effect from more than one study and therefore will have increased statistical power (through larger sample size) and have improved estimates of precision (through smaller standard errors), thus yielding narrower confidence intervals (CIs) for the effect estimate; therefore, the more certain we are that the effect estimate reflects the true effect size. It is important to remember that subgroup and sensitivity analyses are observational associations, not causal, as any observed effect could be due to confounding, bias or chance. [Extracted from the article]
- Subjects :
- *META-analysis
Subjects
Details
- Language :
- English
- ISSN :
- 00070963
- Volume :
- 181
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- British Journal of Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 138896684
- Full Text :
- https://doi.org/10.1111/bjd.18336