An integrated anode based on porous Ni/Cu(OH)2 nanospheres for non-enzymatic glucose sensing.

Novel 3D porous Ni/Cu(OH) 2 nanospheres (Ni/Cu(OH) 2 NS) were directly grown on a Ni foam (NF) via a facile one-step potentiostatic deposition synthesis route. The resultant Ni/Cu(OH) 2 NS possessed an abundance of catalytic which gave them excellent catalytic properties for the electrochemical detection of glucose in alkaline conditions. Using these NS in a promising and integrated non-enzymatic glucose sensor, a high sensitivity of 8722 μA mM−1 cm−2, a low detection limit of 1.27 μM, and a linear detection range from 10 to 1490 μM were obtained at the Ni/Cu(OH) 2 NS/NF anode. Additionally, the proposed sensor exhibited excellent anti-interference capability, good reproducibility, and long duration stability. It was successfully applied to glucose detection in human blood serum, showing excellent effectiveness. • Porous Ni/Cu(OH) 2 nanospheres supported on the Ni foam was fabricated by a facile one-step potentiostatic deposition strategy. • As-prepared Ni/Cu(OH) 2 /NF anode shows excellent catalytic activity to glucose. • The porous Ni/Cu(OH) 2 nanospheres could offer more abundant active sites and easier access to electrolyte. [ABSTRACT FROM AUTHOR]