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Concise and Gram-Scale Total Synthesis of Lansiumamides A and B and Alatamide.
- Source :
-
Molecules . Oct2019, Vol. 24 Issue 20, p3764. 1p. - Publication Year :
- 2019
-
Abstract
- The total synthesis of potent anti-obesity lansiumamide B was accomplished in four steps using commercially available materials. The synthetic strategy, featured with copper-catalyzed Buchwald coupling, is concise, convergent, practical and can be carried out on a one-gram scale. This approach could give either Z- or E-configured enamide moiety in natural products with absolute stereocontrol and was applied in the total synthesis of natural products. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NATURAL products
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 24
- Issue :
- 20
- Database :
- Academic Search Index
- Journal :
- Molecules
- Publication Type :
- Academic Journal
- Accession number :
- 139331703
- Full Text :
- https://doi.org/10.3390/molecules24203764