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Reflux finding score is associated with gastroesophageal flap valve status in patients with laryngopharyngeal reflux disease: a retrospective study.

Authors :
Wu, Wei
Li, Lianyong
Qu, Changmin
Wang, Min
Liang, Shuwen
Gao, Xiaopei
Bao, Xinwei
Wang, Lei
Liu, Hongdan
Han, Haolun
Xu, Bingxin
Zhou, Ying
Li, Baowei
Zhang, Yiyan
Wang, Gang
Zhong, Changqing
Source :
Scientific Reports. 10/31/2019, Vol. 9 Issue 1, pN.PAG-N.PAG. 1p.
Publication Year :
2019

Abstract

Endoscopic grading of gastroesophageal flap valve (GEFV) is simple and reproducible and offers useful information for reflux activity. To investigate the potential correlation between GEFV grading and reflux finding score (RFS) in patients with laryngopharyngeal reflux disease (LPRD), 225 consecutive Patients with suspected LPRD who underwent both routine upper gastrointestinal endoscopy and laryngoscope were enrolled in our study. Patients with a RFS of more than 7 were diagnosed with LPRD. The GEFV was graded as I through IV according to Hill's classification and was classified into two groups: normal GEFV group (grades I and II) and the abnormal GEFV group (grades III and IV). The percent of GEFV grades I to IV was 39.1%, 39.1%, 12.4%, and 9.3%, respectively. Age was significantly related to an abnormal GEFV (p = 0.002). Gender, BMI, smoke and alcohol were not related to GEFV grade. Fifty-one patients (22.67%) had positive RFS. Reflux finding scores were higher in GEFV grades III and IV than I and II (p < 0.05). Endoscopic grading of GEFV is well correlated with reflux finding score in patients with LPRD. This is a simple and useful technique that provides valuable diagnostic information of LPRD. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20452322
Volume :
9
Issue :
1
Database :
Academic Search Index
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
139439074
Full Text :
https://doi.org/10.1038/s41598-019-52349-5