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Preliminary Evaluation of Selected Aptamers against Hantaviruse.

Authors :
Valdez, E. C. N.
Cortez, C. M.
dos Santos Oliveira, R. P. O.
Vidal, S.
Silva, D.
de Lemos, E. R. S.
Missailidis, S. S.
Source :
AIP Conference Proceedings. 2019, Vol. 2186 Issue 1, p130009-1-130009-3. 3p.
Publication Year :
2019

Abstract

Hantavirus is a zoonotic, viral respiratory disease and is recent associated with human diseases that need a qualitative diagnosis method to promote a rational treatment as well as controlling the spread ability of the virus. Thus a early rational treatment is necessary in the outcome of the disease that on a identification etiological agent is essential. This paper shows results obtained from hantavirus aptamers interaction with the hantavirus protein, ANDES solution, throw fluorometric methods, that will assist in the determination of a secure path to aim an identification mechanism to identify the virus. The investigation revels that aptamer C2526 shows a high affinity binding with hantavirus protein, ANDES, being a promise reactive for recognizing assays. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0094243X
Volume :
2186
Issue :
1
Database :
Academic Search Index
Journal :
AIP Conference Proceedings
Publication Type :
Conference
Accession number :
140362405
Full Text :
https://doi.org/10.1063/1.5138058