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In vitro evolution of terminal protein-containing genomes.

Authors :
Esteban, Jose A.
Blanco, Luis
Villar, Laurentino
Salas, Margarita
Source :
Proceedings of the National Academy of Sciences of the United States of America. 04/01/97, Vol. 94 Issue 7, p2921. 6p. 4 Black and White Photographs, 1 Diagram, 3 Graphs.
Publication Year :
1997

Abstract

Demonstrates the use of a self-sustained terminal protein-primed DNA amplification system to describe in vitro evolutionary changes affecting maintenance of the genome size of bacteriophage phi29. Generation and amplification of short palindromic molecules containing an inverted duplication of an original DNA end; Template-switching mechanism.

Details

Language :
English
ISSN :
00278424
Volume :
94
Issue :
7
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
140788
Full Text :
https://doi.org/10.1073/pnas.94.7.2921