537OEvaluating medical oncology outcomes: An Asian lung cancer study.

Background Cancer is a significant public health issue. The need to improve prevention and control programs is especially critical in Asia, where approximately half of all newly diagnosed cancers globally occur. To better understand factors related to aetiology and clinical prognosis, cancer registries have been increasingly integrated within medical oncology. Combining diagnosis, treatment, quality of life and mortality data helps to effectively guide clinical practices that ultimately improve patient care. Methods To examine and compare clinical outcomes in lung cancer patients across settings, a retrospective population-based study was launched in selected Asian countries. All incident cases diagnosed between 2017 – 2019 in Yogyakarta (Indonesia), Penang (Malaysia), Lampang (Thailand) and Singapore will be eligible for inclusion. Using the registry as the study base, details of tumour characteristics including data for survival analyses, molecular testing, stage, performance status and treatments within the first six month will be abstracted from chart reviews. Results For the study period, over 5 000 cases are expected from all four sites: 1 000 from Yogyakarta; 1 000 from Lampang; 650 from Penang; and 3 000 from Singapore. Following a literature review, an initial list of indicators was developed. These were further refined through expert review, to yield a final set of 40 clinical indicators, ranging from diagnosis to palliative care. This presentation will provide an overview of the study, expected outcomes and preliminary results from 50 – 100 cases per site. Conclusions This study will establish methods that allow for clinical information to be integrated with existing population-based cancer registries, permitting comparisons in clinical outcomes for helping to set public policy. Legal entity responsible for the study ESMO. Funding European Society for Medical Oncology. Disclosure All authors have declared no conflicts of interest. [ABSTRACT FROM AUTHOR]