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Targeting Mutant KRAS for Immunogenic Cell Death Induction.
- Source :
-
Trends in Pharmacological Sciences . Jan2020, Vol. 41 Issue 1, p1-3. 3p. - Publication Year :
- 2020
-
Abstract
- Although somatic KRAS mutations are common in human tumors, no inhibitor of mutant KRAS was clinically available until recently. Canon and colleagues describe the ability of a clinically available KRASG12C inhibitor to drive immunogenic cancer cell death, thus constituting a promising combinatorial partner for immune checkpoint blockers. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01656147
- Volume :
- 41
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Trends in Pharmacological Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 140937551
- Full Text :
- https://doi.org/10.1016/j.tips.2019.11.004