Back to Search Start Over

Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells.

Authors :
Wu, Yanan
Meng, Hong-Min
Chen, Juan
Jiang, Kemei
Yang, Ran
Li, Yingying
Zhang, Ke
Qu, Lingbo
Zhang, Xiao-Bing
Li, Zhaohui
Source :
Chemical Communications. 1/11/2020, Vol. 56 Issue 3, p470-473. 4p.
Publication Year :
2020

Abstract

By assembling DNAzyme on DNA nanowires through DNA hybridization, we have developed a novel accelerated DNAzyme-based fluorescent nanoprobe for fast, sensitive and selective detection of miRNA. Moreover, the strategy was successfully applied for in situ imaging of miRNA-21 in different cell lines. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
56
Issue :
3
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
141010203
Full Text :
https://doi.org/10.1039/c9cc08598j