Detection of Six Kinds of Antiphospholipid Antibodies in the Serum of Healthy Volunteers.

Antiphospholipid antibodies are a family of closely related but heterogeneous autoantibodies that may have different biological and pathogenic properties. The article investigates the distribution of six kinds of Antiphospholipid antibodies (aPL) in the serum of healthy volunteers. Whole peripheral blood samples of 82 healthy volunteers were drawn from blood donors with median age of 39.3 years. The findings suggest that healthy volunteers possess aPL. Some aPL are natural autoantibodies that are present in healthy individuals. Other aPL present in sera from healthy individuals are those that may be uncovered by heating sera at 56 degrees Celsius for 30 minutes.