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Long‐term functional and oncological outcomes of nerve‐sparing and prostate capsule‐sparing cystectomy: a single‐centre experience.
- Source :
-
BJU International . Feb2020, Vol. 125 Issue 2, p253-259. 7p. - Publication Year :
- 2020
-
Abstract
- Objectives: To evaluate the technical feasibility, oncological and functional outcomes of nerve sparing cystoprostatectomy (NSCP) and prostate capsule‐sparing cystectomy (PCSC) for the treatment of organ‐confined bladder cancer at a single referral centre. Patients and Methods: From April 2001 to June 2012, 60 patients underwent PCSC and 47 were treated with NSCP. Inclusion criteria for PCSC were: fully informed consent for the well‐motivated patient; negative transurethral resection of the bladder neck; normal prostatic specific antigen (PSA) level (defined as <4 ng/dL during the first year of the study, which was later lowered to 2.5 ng/dL); and normal transrectal ultrasonography, with biopsy for any suspicious nodule. Patients received a complete oncological and functional follow‐up. The Kaplan–Meier method was used to depict survival outcomes after surgery. Results: After a median follow‐up of 73 and 62 months for PCSC and NSCP, respectively, the 5‐year cancer‐specific survival was 90% for the PCSC group and 78% for the NSCP group (P = 0.055). Considering complications within 30 days after surgery, 13% and 21% patients had Clavien ≥III complications in the PCSC and NSCP groups, respectively (P = 0.2). For functional outcomes, at 3 months after surgery, 54 (90%) and 24 (51%) patients reported full recovery of daytime urinary continence in the PCSC and NSCP groups, respectively (P < 0.001); and for erectile function recovery, 32 (53%) and four (9%) patients in the PCSC group and in the NSCP group were respectively potent without any treatment (P < 0.001). Conclusions: NSCP and PCSC are appropriate for a subset of patients with bladder cancer, with excellent oncological and functional results. These surgical procedures should be proposed to well‐motivated patients. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14644096
- Volume :
- 125
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- BJU International
- Publication Type :
- Academic Journal
- Accession number :
- 141206643
- Full Text :
- https://doi.org/10.1111/bju.14850