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Male patient with metastatic stage IV breast cancer achieves complete remission on second line Abemaciclib, Fulvestrant and Leuprolide: A case report.

Authors :
Hansra, Damien
Jackson, Shirelle
Sequeira, Judy
Vazirani, Rajendra
Alvarez, Ricardo
Source :
Molecular & Clinical Oncology. Feb2020, Vol. 12 Issue 2, p120-125. 6p.
Publication Year :
2020

Abstract

Male breast cancer occurs rarely, comprising <1% of breast cancers. Due to the low incidence of male breast cancer, clinical trials of this disease are lacking. Therefore, therapeutic strategies utilized in the management of female breast cancer are often applied to male patients with breast cancer. Specifically, clinical outcomes using CDK 4/6 inhibitors require further investigation in male patients. To the best of our knowledge, the present report presents the first known case of a male patient treated with second line Abemaciclib, Lupron and Fulvestrant, producing complete remission. To the best of our knowledge this is also the first report of complete remission in a male breast cancer patient with a regimen utilizing a CDK 4/6 inhibitor. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20499450
Volume :
12
Issue :
2
Database :
Academic Search Index
Journal :
Molecular & Clinical Oncology
Publication Type :
Academic Journal
Accession number :
141233550
Full Text :
https://doi.org/10.3892/mco.2019.1955