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Predictors of in-hospital mortality following hypoxic-ischemic brain injury: a population-based study.
- Source :
-
Brain Injury . 2020, Vol. 34 Issue 2, p178-186. 9p. - Publication Year :
- 2020
-
Abstract
- Objective: To identify predictors of in-hospital mortality following Hypoxic-Ischemic Brain Injury (HIBI) using the Anderson Behavioral Model. Design and Setting: Population based retrospective cohort study in Ontario, Canada with data collected between 1 April 2002 and 31 March 2017. Patients: Adult patients aged 20 years and older with HIBI-related acute care admission were identified in the health administrative data. Multivariable cox proportional hazard regression models were used to identify predisposing, need and enabling factors that predict in-hospital mortality. Results: Of the 7492 patients admitted to acute care with HIBI, the in-hospital mortality rate was 71%. The predisposing factors associated with mortality were female sex (HR, 1.16; 95% CI, 1.10–1.23) and older age (65–79 vs. 20–34: HR, 1.17; 95% CI, 1.02–1.35). The need factors associated with mortality were the presence of COPD (HR, 1.10; 95% CI, 1.02–1.17), psychiatric illness (HR, 1.13; 95% CI, 1.05–1.20) injury due to cardiac illness (HR, 1.19; 95% CI, 1.12–1.26) and longer emergency department length of stay. Having spending any time in an alternate level of care and the application of tracheotomy procedures were found to reduce mortality.Conclusions: The acute/critical care centers need to consider these findings to adopt prevention strategies targeting reduced in-hospital mortality. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BRAIN injuries
*CONFIDENCE intervals
*CRITICAL care medicine
*LENGTH of stay in hospitals
*HOSPITAL admission & discharge
*HOSPITAL emergency services
*LONGITUDINAL method
*OBSTRUCTIVE lung diseases
*MENTAL illness
*MULTIVARIATE analysis
*PATIENTS
*REGRESSION analysis
*RISK assessment
*TRACHEOTOMY
*PROPORTIONAL hazards models
*RETROSPECTIVE studies
*CEREBRAL anoxia-ischemia
*HOSPITAL mortality
*ODDS ratio
*DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 02699052
- Volume :
- 34
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Brain Injury
- Publication Type :
- Academic Journal
- Accession number :
- 141290790
- Full Text :
- https://doi.org/10.1080/02699052.2019.1683897