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Update 2020: nomenclature and listing of celiac disease–relevant gluten epitopes recognized by CD4+ T cells.

Authors :
Sollid, Ludvig M.
Tye-Din, Jason A.
Qiao, Shuo-Wang
Anderson, Robert P.
Gianfrani, Carmen
Koning, Frits
Source :
Immunogenetics. Feb2020, Vol. 72 Issue 1/2, p85-88. 4p.
Publication Year :
2020

Abstract

Celiac disease is caused by an abnormal intestinal T cell response to cereal gluten proteins. The disease has a strong human leukocyte antigen (HLA) association, and CD4+ T cells recognizing gluten epitopes presented by disease-associated HLA-DQ allotypes are considered to be drivers of the disease. This paper provides an update of the currently known HLA-DQ restricted gluten T cell epitopes with their names and sequences. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00937711
Volume :
72
Issue :
1/2
Database :
Academic Search Index
Journal :
Immunogenetics
Publication Type :
Academic Journal
Accession number :
141292300
Full Text :
https://doi.org/10.1007/s00251-019-01141-w