Molybdenum sulfide-based electrochemical platform for high sensitive detection of taxifolin in Chinese medicine.

MoS 2 and nitrogen doped active carbon composite (MoS 2 /ANC) is fabricated to detect taxifolin and exhibits superior redox current response and decreased redox potential difference. Further investigation reveals that the kinetic process of the redox reaction of taxifolin on MoS 2 /ANC electrode is controlled by both adsorption and diffusion process. Under the optimum conditions, the redox peak currents linearly relate with the concentration of taxifolin in the range of 1 × 10−9–1 × 10−6 mol L−1, accompanied by the low detection limit (3 × 10−10 mol L−1). Meanwhile, outstanding selectivity, stability and repeatability are also obtained at MoS 2 /ANC electrode. At last, the proposed method is applied to quantitatively detect taxifolin in fructus polygoni orientalis and satisfactory results have been achieved. Image 1 • The kinetic process of the redox reaction of taxifolin on MoS 2 /ANC is controlled by both adsorption and diffusion. • MoS 2 /ANC sensor displays wide linear range and low detection limit. • MoS 2 /ANC reveals outstanding selectivity in fructus polygoni orientalis detection. [ABSTRACT FROM AUTHOR]