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Polymer surface micropatterning by plasma and VUV-photochemical modification for controlled cell culture
- Source :
-
Applied Surface Science . Aug2004, Vol. 235 Issue 4, p395-405. 11p. - Publication Year :
- 2004
-
Abstract
- Surface chemical micropatterns have been created by both low-pressure “cold” plasma, and by vacuum ultraviolet (VUV) photochemical modification of biaxially oriented polypropylene (BOPP). Oxygen, nitrogen and ammonia plasma, and ammonia-VUV treatments have been performed, including through metal masks with micrometer-sized openings. Surface analysis by X-ray photoelectron spectroscopy (XPS) has been used to characterise the modified surfaces. Imaging time-of-flight secondary ion mass spectrometry (ToF-SIMS) of partially masked regions has demonstrated the ability to produce micrometer scale chemical patterns of oxygen and nitrogen-containing functionalities, for example, hydroxyl and amine groups, contrasted with untreated hydrocarbon regions. Nitrogen and ammonia plasma patterned surfaces, and ammonia-VUV patterned surfaces have been used to control the immobilisation and growth of foetal bovine cerebellar neurons and growth plate chondrocytes cells in culture. [Copyright &y& Elsevier]
- Subjects :
- *NITROGEN compounds
*SURFACE analysis
*ORGANIC compounds
*MOLECULAR orbitals
Subjects
Details
- Language :
- English
- ISSN :
- 01694332
- Volume :
- 235
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Applied Surface Science
- Publication Type :
- Academic Journal
- Accession number :
- 14187984
- Full Text :
- https://doi.org/10.1016/j.apsusc.2004.02.058