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The role of innate immunity in asthma development and protection: Lessons from the environment.
- Source :
-
Clinical & Experimental Allergy . Mar2020, Vol. 50 Issue 3, p282-290. 9p. 2 Diagrams. - Publication Year :
- 2020
-
Abstract
- Asthma, a complex, chronic disease characterized by airway inflammation, hyperresponsiveness and remodelling, affects over 300 million people worldwide. While the disease is typically associated with exaggerated allergenāinduced type 2 immune responses, these responses are strongly influenced by environmental exposures that stimulate innate immune pathways capable of promoting or protecting from asthma. The dual role played by innate immunity in asthma pathogenesis offers multiple opportunities for both research and clinical interventions and is the subject of this review. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NATURAL immunity
*ASTHMA
*PATHOLOGY
*ENVIRONMENTAL exposure
*IMMUNE response
*ATOPY
Subjects
Details
- Language :
- English
- ISSN :
- 09547894
- Volume :
- 50
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Clinical & Experimental Allergy
- Publication Type :
- Academic Journal
- Accession number :
- 141957590
- Full Text :
- https://doi.org/10.1111/cea.13508