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Hourly Fluid Balance in Patients Receiving Continuous Renal Replacement Therapy.
- Source :
-
Blood Purification . 2020, Vol. 49 Issue 1/2, p93-101. 9p. - Publication Year :
- 2020
-
Abstract
- Introduction: Little is known about early (first 48 h) hourly and cumulative fluid balance (FB) during continuous renal replacement therapy (CRRT). Objectives: To study the characteristics and outcome associations of early hourly and cumulative FB. Methods: We studied FB in CRRT patients (2016–2018). Results: Among 350 patients, mean hourly FB became negative after 20 CRRT hours, but within 6 CRRT hours in patients with baseline fluid overload. A negative early FB was never achieved in patients receiving vasopressor therapy (p < 0.001). Mortality was 31%. The percentage of hourly negative FB was independently associated with decreased ICU mortality. A time-weighted hourly FB between 18.5 and –33 mL/h was also significantly and independently associated with decreased mortality. Conclusions: In CRRT patients, an early FB conservative approach is possible, modulated by patient characteristics, and associated with a low mortality. Moreover, avoidance of an early positive FB is associated with decreased mortality. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MORTALITY
*PATIENTS
*FLUIDS
Subjects
Details
- Language :
- English
- ISSN :
- 02535068
- Volume :
- 49
- Issue :
- 1/2
- Database :
- Academic Search Index
- Journal :
- Blood Purification
- Publication Type :
- Academic Journal
- Accession number :
- 142083491
- Full Text :
- https://doi.org/10.1159/000503771