Back to Search
Start Over
Synthesis of N‐Sulfonyl Pyrazoles Through Cyclization Reactions of Sulfonyl Hydrazines with Enaminones Promoted by p‐TSA.
- Source :
-
European Journal of Organic Chemistry . 3/8/2020, Vol. 2020 Issue 9, p1154-1159. 6p. - Publication Year :
- 2020
-
Abstract
- A strategy for the rapid synthesis of 3‐substituted N‐sulfonyl pyrazoles via p‐TSA‐promoted cyclization reactions of sulfonyl hydrazines with N,N‐dimethyl enaminones has been developed. This method achieves both the formation of pyrazole ring and the continued retention of sulfonyl group, providing a series of 3‐substituted N‐sulfonyl pyrazoles in moderate to good yields with good functional group tolerance, easily available starting materials, and can be scaled‐up. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PYRAZOLES
*HYDRAZINE
*SULFONYL compounds
*SULFONYL group
*FUNCTIONAL groups
Subjects
Details
- Language :
- English
- ISSN :
- 1434193X
- Volume :
- 2020
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- European Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 142100933
- Full Text :
- https://doi.org/10.1002/ejoc.201901886